A new study suggests high chilli pepper consumption may be associated with an increased risk of certain gastrointestinal cancers, particularly esophageal cancer. However, researchers emphasize the findings do not prove a direct causal link.

Study Findings on Chilli Peppers and Cancer Risk

A review published in Frontiers in Nutrition analyzed 14 observational studies involving over 11,000 participants, including more than 5,000 with gastrointestinal cancers. The research compared high chilli consumers to those with low intake, concluding that chilli peppers "may be a risk factor" for some digestive cancers.

Why the Results Vary by Region

The link between chilli consumption and cancer risk differed across regions. Studies in Asia, Africa, and North America reported higher risks among heavy chilli eaters, while research from Europe and South America showed no increased risk or possible protective effects. Factors like chilli type, cooking methods, and genetic differences may explain these variations.

Understanding Gastrointestinal Cancers

Gastrointestinal cancers affect digestion-related organs, including the esophagus, stomach, and colon. They account for nearly 5 million new cases annually and one-third of cancer deaths worldwide. Many are diagnosed at advanced stages, prompting research into dietary influences.

Chilli peppers contain capsaicin, which has shown conflicting effects in lab studies—reducing inflammation in some cases but potentially irritating tissue in others. Scientists note that stronger studies are needed to clarify the relationship between chilli intake and cancer.